
Effectiveness of operative and nonoperative therapy in endomyocardial fibrosis
1989; Elsevier BV; Volume: 63; Issue: 17 Linguagem: Inglês
10.1016/0002-9149(89)90193-8
ISSN1879-1913
AutoresCharles Mady, Antônio Carlos Pereira Barretto, Sérgio Almeida de Oliveira, Noedir Antônio Groppo Stolf, Giovanni Bellotti, Adib Domingos Jatene, F Pileggi,
Tópico(s)Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
ResumoEndomyocardial fibrosis (EMF) is an infrequent disease in Brazil, and its etiology is still unknown. The disease is characterized by fibrosis of endocardium and adjacent myocardium, mainly in the inflow tract of the ventricles. Thus, it is a restrictive syndrome.1 The fibrous tissue generally involves the papillary muscles, leading to atrioventricular valve dysfunctions. These dysfunctions, associated with the restriction in ventricular filling, frequently cause severe hemodynamic disturbances with a poor prognosis.2,3 Therefore, choice of the best treatment—clinical or surgical—is frequently crucial. The natural history of clinically treated patients shows high short-term mortality rate,4 but surgical mortality—which has been decreasing—is still high.5–10 In this retrospective study, we describe the results obtained in patients treated clinically and surgically in our institution.
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