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Tc-99m Sestamibi and Other Agents in the Detection of Metastatic Medullary Carcinoma of the Thyroid

1993; Lippincott Williams & Wilkins; Volume: 18; Issue: 8 Linguagem: Inglês

10.1097/00003072-199308000-00005

1536-0229

GILLES LEBOUTHILLIER, JACQUES MORAIS, Michel Picard, D Picard, R Chartrand, P D'Amour,

Peptidase Inhibition and Analysis

The 10-year survival rate for medullary carcinoma of the thyroid (MCT) is 50%; thus, good tumor-seeking radiopharmaceuticals are needed to localize foci of recurrence and metastasis during follow-up. Two patients with metastatic MCT were studied with Tl-201, l-131 MIBG, Tc-99m (V)-DMSA, and Tc-99m MIBI. A SPECT study with the latter agent allowed the visualization and precise localization of a metastatic mediastinal lymph node. More studies need to be done to evaluate the role of Tc-99m MIBI in the detection of recurrence and metastases of MCT.