Portal de Periódicos da CAPES

Synthesis of deuterated 4,4′‐diaminodiphenylsulfone (Dapsone) and related analogs

2002; Wiley; Volume: 46; Issue: 2 Linguagem: Inglês

10.1002/jlcr.649

1099-1344

Peter M. Gannett, Edward M. Johnson, Michael Grimes, Alan L. Myers, Robert E. Deavers, Timothy S. Tracy,

Chemical synthesis and alkaloids

Abstract A general scheme for the synthesis of 4,4′‐diaminodiphenylsulfone‐d 5 (Dapsone) from aniline‐d 5 is described. The method may have general application and the preparation of the related analogs, 4,4′‐dimethylaminodiphenyl sulfone from aniline‐d 5 and 4,4′‐dimethoxydiphenyl sulfone from phenol‐d 5 , is also described. Copyright © 2002 John Wiley & Sons, Ltd.