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Dominant‐negative form of the Pax6 homolog eyeless for tissue‐specific loss‐of‐function studies in the developing eye and brain in drosophila

2002; Wiley; Volume: 34; Issue: 1-2 Linguagem: Inglês

10.1002/gene.10140

1526-968X

Teruyuki Niimi, Jason Clements, W J Gehring, Patrick Callaerts,

Chromosomal and Genetic Variations

genesisVolume 34, Issue 1-2 p. 74-75 UAS LinesFree Access Dominant-negative form of the Pax6 homolog eyeless for tissue-specific loss-of-function studies in the developing eye and brain in drosophila T. Niimi, T. Niimi Department of Cell Biology, Biozentrum, Basel, SwitzerlandSearch for more papers by this authorJ. Clements, J. Clements Department of Biology and Biochemistry, University of Houston, Houston, Texas, USASearch for more papers by this authorW.J. Gehring, W.J. Gehring Department of Cell Biology, Biozentrum, Basel, SwitzerlandSearch for more papers by this authorP. Callaerts, Corresponding Author P. Callaerts [email protected] Department of Biology and Biochemistry, University of Houston, Houston, Texas, USADepartment of Biology and Biochemistry, University of Houston, 369 Science and Research, Building 2, Houston, TX 77204-5001Search for more papers by this author T. Niimi, T. Niimi Department of Cell Biology, Biozentrum, Basel, SwitzerlandSearch for more papers by this authorJ. Clements, J. Clements Department of Biology and Biochemistry, University of Houston, Houston, Texas, USASearch for more papers by this authorW.J. Gehring, W.J. Gehring Department of Cell Biology, Biozentrum, Basel, SwitzerlandSearch for more papers by this authorP. Callaerts, Corresponding Author P. Callaerts [email protected] Department of Biology and Biochemistry, University of Houston, Houston, Texas, USADepartment of Biology and Biochemistry, University of Houston, 369 Science and Research, Building 2, Houston, TX 77204-5001Search for more papers by this author First published: 12 September 2002 https://doi.org/10.1002/gene.10140Citations: 10AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. LITERATURE CITED Brand AH, Perrimon N. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401– 415. Callaerts P, Leng S, Clements J, Benassayag C, Cribbs D, Kang YY, Walldorf U, Fischbach K-F, Strauss R. 2001. Drosophila Pax-6/eyeless is essential for normal adult brain structure and function. J Neurobiol 46: 73– 88. Conlon FL, Sedgwick SG, Weston KM, Smith JC. 1996. Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm. Development 122: 2427– 2435. Connolly JB, Roberts IJ, Armstrong JD, Kaiser K, Forte M, Tully T, O'Kane CJ. 1996. Associative learning disrupted by impaired Gs signaling in the mushroom bodies. Science 274: 2104– 2107. Glavic A, Gomez-Skarmeta JL, Mayor R. 2001. Xiro-1 controls mesoderm patterning by repressing bmp-4 expression in the Spemann organizer. Dev Dyn 222: 368– 376. Grenningloh G, Rehm EJ, Goodman CS. 1991. Genetic analysis of growth cone guidance in Drosophila: fasciclin II functions as a neuronal recognition molecule. Cell 67: 45– 57. Gross JM, McClay DR. 2001. The role of Brachyury (T) during gastrulation movements in the sea urchin Lytechinus variegatus. Dev Biol 239: 132– 147. Halder G, Callaerts P, Gehring WJ. 1995. Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. Science 267: 1788– 1792. Hauck B, Gehring WJ, Walldorf U. 1999. Functional analysis of an eye specific enhancer of the eyeless gene in Drosophila. Proc Natl Acad Sci USA 96: 564– 569. Kurusu M, Nagao T, Walldorf U, Flister S, Gehring WJ, Furukubo-Tokunaga K. 2000. Genetic control of development of the mushroom bodies, the associative learning centers in the Drosophila brain, by the eyeless, twin of eyeless, and Dachshund genes. Proc Natl Acad Sci USA 97: 2140– 2144. Noveen A, Daniel A, Hartenstein V. 2000. Early development of the Drosophila mushroom body: the roles of eyeless and dachshund. Development 127: 3475– 3488. Quiring R, Walldorf U, Kloter U, Gehring, WJ. 1994. Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science 265: 785– 789. Rubin GM, Spradling AC. 1982. Genetic transformation of Drosophila with transposable element vectors. Science 218: 348– 353. Citing Literature Volume34, Issue1-2Special Issue: GAL4/UAS in Drosophila September ‐ October 2002Pages 74-75 ReferencesRelatedInformation