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Synthesis of yuehchukene and some analogues a general approach

1992; Elsevier BV; Volume: 48; Issue: 4 Linguagem: Inglês

10.1016/s0040-4020(01)88135-7

1464-5416

Jan Bergman, Lennart Venemalm,

Synthetic Organic Chemistry Methods

Yuehchukene and a number of structural analogues have been synthesized by intromolecular ring closure of α,β-unsaturated 2-acylindoles in the key step. Reduction of the resulting cyclopent[b]indol-3-one derivatives, followed by acid-catalyzed incorporation of a second indole unit, gave the title compounds.