Myocardial stunning and hibernation. The physiology behind the colloquialisms.
1991; Lippincott Williams & Wilkins; Volume: 83; Issue: 2 Linguagem: Inglês
10.1161/01.cir.83.2.681
ISSN1524-4539
Autores Tópico(s)Pain Mechanisms and Treatments
ResumoHomeCirculationVol. 83, No. 2Myocardial stunning and hibernation. The physiology behind the colloquialisms. Free AccessAbstractPDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessAbstractPDF/EPUBMyocardial stunning and hibernation. The physiology behind the colloquialisms. E Marban E MarbanE Marban Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Md 21205. Originally published1 Feb 1991https://doi.org/10.1161/01.CIR.83.2.681Circulation. 1991;83:681–688 eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetailsCited By Seppelt P, De Rosa R, Mas-Peiro S, Zeiher A and Vasa-Nicotera M (2020) Early hemodynamic changes after transcatheter aortic valve implantation in patients with severe aortic stenosis measured by invasive pressure volume loop analysis, Cardiovascular Intervention and Therapeutics, 10.1007/s12928-020-00737-4, 37:1, (191-201), Online publication date: 1-Jan-2022. Heusch G (2021) Myocardial stunning and hibernation revisited, Nature Reviews Cardiology, 10.1038/s41569-021-00506-7, 18:7, (522-536), Online publication date: 1-Jul-2021. Yang Y, Schena G, Wang T and Houser S (2021) Postsurgery echocardiography can predict the amount of ischemia-reperfusion injury and the resultant scar size, American Journal of Physiology-Heart and Circulatory Physiology, 10.1152/ajpheart.00672.2020, 320:2, (H690-H698), Online publication date: 1-Feb-2021. Mehrani M, Abbasi S, Amin A, Kassaian S and Mahmoudi M (2020) Ischemic cardiomyopathy Nanomedicine for Ischemic Cardiomyopathy, 10.1016/B978-0-12-817434-0.00001-5, (1-8), . Piñeiro D and Cuenca G (2019) Viabilidad miocárdica por ecocardiografía, Revista Colombiana de Cardiología, 10.1016/j.rccar.2018.10.019, 26, (19-30), Online publication date: 1-Jul-2019. Verma S, Burkhoff D and O'Neill W (2016) Avoiding hemodynamic collapse during high-risk percutaneous coronary intervention: Advanced hemodynamics of impella support, Catheterization and Cardiovascular Interventions, 10.1002/ccd.26795, 89:4, (672-675), Online publication date: 1-Mar-2017. Slavich M, Maranta F, Fumero A, Godino C, Giannini F, Oppizzi M, Colombo A, Fragasso G and Margonato A (2016) Long-Term Preservation of Left Ventricular Systolic Function in Patients With Refractory Angina Pectoris and Inducible Myocardial Ischemia on Optimal Medical Therapy, The American Journal of Cardiology, 10.1016/j.amjcard.2016.02.028, 117:10, (1558-1561), Online publication date: 1-May-2016. Yadav H, Varshney V, Singh N and Sharma P (2015) Quercetin: A Phytoestrogen Attenuate GSK-3β Inhibitors Induced Delayed Cardioprotection in Diabetic Rat Heart, Pharmacologia, 10.5567/pharmacologia.2015.293.299, 6:7, (293-299), Online publication date: 1-Jul-2015. Abdou M, Engberding N and Wenger N (2015) Pathophysiology and Management of Myocardial Infarction Pathophysiology and Pharmacotherapy of Cardiovascular Disease, 10.1007/978-3-319-15961-4_20, (397-424), . Willerson J and Armstrong P (2015) Coronary Heart Disease Syndromes: Pathophysiology and Clinical Recognition Coronary Artery Disease, 10.1007/978-1-4471-2828-1_15, (365-407), . Bayeva M, Sawicki K, Butler J, Gheorghiade M and Ardehali H (2014) Molecular and Cellular Basis of Viable Dysfunctional Myocardium, Circulation: Heart Failure, 7:4, (680-691), Online publication date: 1-Jul-2014. Zima A, Pabbidi M, Lipsius S and Blatter L (2013) Effects of mitochondrial uncoupling on Ca 2+ signaling during excitation-contraction coupling in atrial myocytes , American Journal of Physiology-Heart and Circulatory Physiology, 10.1152/ajpheart.00932.2012, 304:7, (H983-H993), Online publication date: 1-Apr-2013. Rosu C, Laflamme M, Perrault-Hebert C, Carrier M and Perrault L (2012) Decreased incidence of low output syndrome with a switch from tepid to cold continuous minimally diluted blood cardioplegia in isolated coronary artery bypass grafting, Interactive CardioVascular and Thoracic Surgery, 10.1093/icvts/ivs294, 15:4, (655-660), Online publication date: 1-Oct-2012. Yadav H, Singh M and Sharma P (2012) Pharmacological inhibition of GSK-3β produces late phase of cardioprotection in hyperlipidemic rat: possible involvement of HSP 72, Molecular and Cellular Biochemistry, 10.1007/s11010-012-1386-8, 369:1-2, (227-233), Online publication date: 1-Oct-2012. Mullens W and Starling R (2011) Surgical Treatment of Chronic Heart Failure Heart Failure: A Companion to Braunwald's Heart Disease, 10.1016/B978-1-4160-5895-3.10055-5, (802-817), . Ristagno G, Tantillo S, Sun S, Weil M and Tang W (2010) Hypothermia improves ventricular myocyte contractility under conditions of normal perfusion and after an interval of ischemia, Resuscitation, 10.1016/j.resuscitation.2010.03.016, 81:7, (898-903), Online publication date: 1-Jul-2010. Yang H, Youn Y and Yoo K (2010) Correlation of Akinesia With Graft Patency and Cardiac Enzyme After Off-Pump Coronary Artery Bypass Graft Surgery, Circulation Journal, 10.1253/circj.CJ-09-0857, 74:8, (1564-1569), . Chmayssani M, Lazar R, Hirsch J and Marshall R (2009) Reperfusion normalizes motor activation patterns in large-vessel disease, Annals of Neurology, 10.1002/ana.21554, 65:2, (203-208), Online publication date: 1-Feb-2009. Hollenberg S and Parrillo J (2008) Cardiogenic Shock Critical Care Medicine, 10.1016/B978-032304841-5.50025-X, (423-438), . Brodoefel H, Reimann A, Klumpp B, Fenchel M, Heuschmid M, Burgstahler C, Schroeder S, Miller S, Claussen C, Scheule A and Kopp A (2007) Sixty-four-slice CT in the assessment of global and regional left ventricular function: Comparison with MRI in a porcine model of acute and subacute myocardial infarction, European Radiology, 10.1007/s00330-007-0673-3, 17:11, (2948-2956), Online publication date: 9-Oct-2007. Comas G, Esrig B and Oz M (2007) Surgery for Myocardial Salvage in Acute Myocardial Infarction and Acute Coronary Syndromes, Heart Failure Clinics, 10.1016/j.hfc.2007.04.006, 3:2, (181-210), Online publication date: 1-Apr-2007. Willerson J, Maseri A and Armstrong P (2007) Coronary Heart Disease Syndromes: Pathophysiology and Clinical Recognition Cardiovascular Medicine, 10.1007/978-1-84628-715-2_31, (667-698), . Редакционная С (2006) Острая сердечная недостаточность: рекомендациипо диагностике и лечению, PULMONOLOGIYA, 10.18093/0869-0189-2006-1-19-56:1, (19-56) Hasegawa H, Takano H, Iwanaga K, Ohtsuka M, Qin Y, Niitsuma Y, Ueda K, Toyoda T, Tadokoro H and Komuro I (2006) Cardioprotective Effects of Granulocyte Colony-Stimulating Factor in Swine With Chronic Myocardial Ischemia, Journal of the American College of Cardiology, 10.1016/j.jacc.2005.09.048, 47:4, (842-849), Online publication date: 1-Feb-2006. (2005) Guías de Práctica Clínica sobre el diagnóstico y tratamiento de la insuficiencia cardíaca aguda. Versión resumida, Revista Española de Cardiología, 10.1157/13073896, 58:4, (389-429), Online publication date: 1-Apr-2005. Hailer B, Van Leeuwen P, Chaikovsky I, Auth-Eisernitz S, Schafer H and Gronemeyer D (2005) The Value of Magnetocardiography in the Course of Coronary Intervention, Annals of Noninvasive Electrocardiology, 10.1111/j.1542-474X.2005.05625.x, 10:2, (188-196), Online publication date: 1-Apr-2005. (2005) Guías de Práctica Clínica sobre el diagnóstico y tratamiento de la insuficiencia cardíaca aguda. Versión resumida, Revista Española de Cardiología (English Edition), 10.1016/S1885-5857(06)60670-1, 58:4, (389-429), Online publication date: 1-Apr-2005. Yao S and Chaudhry F (2005) Assessment of Myocardial Viability with Dobutamine Stress Echocardiography in Patients with Ischemic Left Ventricular Dysfunction, Echocardiography, 10.1111/j.0742-2822.2005.04030.x, 22:1, (71-83), Online publication date: 1-Jan-2005. Reading S, Murrant C and Barclay J (2004) Positive inotropism in mammalian skeletal muscle in vitro during and after fatigue, Canadian Journal of Physiology and Pharmacology, 10.1139/y04-019, 82:4, (249-261), Online publication date: 1-Apr-2004. Güney M and Eren E (2004) Revascularization of multiple bypassable extended right coronary arteries, The Journal of Thoracic and Cardiovascular Surgery, 10.1016/j.jtcvs.2003.07.019, 127:4, (1133-1138), Online publication date: 1-Apr-2004. Bajraktari G, Qirko S, Fusco R, Milazzo A, Xhaxho B and Pezzano A (2003) Transmitral pulsed-Doppler echocardiography is a more accurate technique compared with two-dimensional echocardiography using dobutamine, in patients with one vessel coronary artery disease, European Journal of Heart Failure, 10.1016/S1388-9842(02)00030-2, 5:1, (63-72), Online publication date: 1-Jan-2003. Min J, Liao H, Wang J, Sullivan M, Ito T and Morgan J (2016) Genistein Attenuates Postischemic Depressed Myocardial Function by Increasing Myofilament Ca 2+ Sensitivity in Rat Myocardium 1 , Experimental Biology and Medicine, 10.1177/153537020222700812, 227:8, (632-638), Online publication date: 1-Sep-2002. Yamaguchi H, Weil M, Tang W, Kamohara T, Jin X and Bisera J (2002) Myocardial dysfunction after electrical defibrillation, Resuscitation, 10.1016/S0300-9572(02)00149-1, 54:3, (289-296), Online publication date: 1-Sep-2002. White D, Maass D, Sanders B and Horton J (2002) Cardiomyocyte intracellular calcium and cardiac dysfunction after burn trauma, Critical Care Medicine, 10.1097/00003246-200201000-00003, 30:1, (14-22), Online publication date: 1-Jan-2002. Pellis T and Tang W (2002) Myocardial Preservation during Cardiopulmonary Resuscitation Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E., 10.1007/978-88-470-2099-3_6, (75-85), . Stamm C, Friehs I, Cowan D, Cao-Danh H, Noria S, Munakata M, McGowan F and del Nido P (2001) Post-ischemic PKC inhibition impairs myocardial calcium handling and increases contractile protein calcium sensitivity, Cardiovascular Research, 10.1016/S0008-6363(01)00249-8, 51:1, (108-121), Online publication date: 1-Jul-2001., Online publication date: 1-Jul-2001. Schipke J and Birkenkamp-Demtröder K (2001) Another view of myocardial hibernation, International Journal of Cardiology, 10.1016/S0167-5273(01)00399-0, 79:1, (13-17), Online publication date: 1-Jun-2001. Snoeckx L, Cornelussen R, Van Nieuwenhoven F, Reneman R and Van der Vusse G (2001) Heat Shock Proteins and Cardiovascular Pathophysiology, Physiological Reviews, 10.1152/physrev.2001.81.4.1461, 81:4, (1461-1497), Online publication date: 10-Jan-2001. Hunter W (2000) ROLE OF MYOFILAMENTS AND CALCIUM HANDLING IN LEFT VENTRICULAR RELAXATION, Cardiology Clinics, 10.1016/S0733-8651(05)70155-7, 18:3, (443-457), Online publication date: 1-Aug-2000. Thompson M, Kliewer A, Maass D, Becker L, White D, Bryant D, Arteaga G, Horton J and Giroir B (2000) Increased Cardiomyocyte Intracellular Calcium during Endotoxin-Induced Cardiac Dysfunction in Guinea Pigs, Pediatric Research, 10.1203/00006450-200005000-00019, 47:5, (669-676), Online publication date: 1-May-2000. Köppel H, Pilger E and Gasser R (2000) Cellular Mechanisms of Myocardial Hibernation, Stunning, and Ischemic Preconditioning Textbook of Angiology, 10.1007/978-1-4612-1190-7_7, (106-111), . Wu K, Rochitte C and Lima J (1999) Magnetic resonance imaging in acute myocardial infarction, Current Opinion in Cardiology, 10.1097/00001573-199911000-00005, 14:6, (480), Online publication date: 1-Nov-1999. Van Gelder I, Tuinenburg A, Schoonderwoerd B, Tieleman R and Crijns H (1999) Pharmacologic versus direct-current electrical cardioversion of atrial flutter and fibrillation, The American Journal of Cardiology, 10.1016/S0002-9149(99)00715-8, 84:9, (147-151), Online publication date: 1-Nov-1999. Chandrashekhar Y, Prahash A, Sen S, Gupta S and Anand I (1999) Cardiomyocytes from hearts with left ventricular dysfunction after ischemia-reperfusion do not manifest contractile abnormalities, Journal of the American College of Cardiology, 10.1016/S0735-1097(99)00222-3, 34:2, (594-602), Online publication date: 1-Aug-1999. Yamaguchi H and Weil M (1999) Postresuscitation Myocardial Dysfunction Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E., 10.1007/978-88-470-2145-7_5, (69-75), . Merdler A, Halon D, Flugelman M and Lewis B (1999) Use of Calcium Antagonists After Myocardial Infarction: Focus on the DEFIANT Studies Nisoldipine Coat-Core, 10.1007/978-3-642-60220-7_5, (47-60), . Caesar R (1999) Herz Pathologie, 10.1007/978-3-642-58620-0_7, (103-276), . Tveita T, Ytrehus K, Myhre E and Hevrøy O (1998) Left ventricular dysfunction following rewarming from experimental hypothermia, Journal of Applied Physiology, 10.1152/jappl.1998.85.6.2135, 85:6, (2135-2139), Online publication date: 1-Dec-1998. Schrader J and Decking U (1998) Sites and mechanism of adenosine formation in the cardiovascular system, Drug Development Research, 10.1002/(SICI)1098-2299(199811/12)45:3/4 3.0.CO;2-0, 45:3-4, (288-294), Online publication date: 1-Nov-1998. HEUSCH G (1998) Hibernating Myocardium, Physiological Reviews, 10.1152/physrev.1998.78.4.1055, 78:4, (1055-1085), Online publication date: 1-Oct-1998. Piriou V, Lehot J, Obadia J, Terrenoire C and Janier M (1998) Sidération et hibernation myocardique: mise à jour pour l'anesthésiste-réanimateurStunned and hibernating myocardium: an update for the anaesthetists, Canadian Journal of Anaesthesia, 10.1007/BF03012309, 45:10, (997-1010), Online publication date: 1-Oct-1998. Schaefer J, Nierhaus K, Lohff B, Peters T, Schaefer T and Vos R (1998) Mechanisms of autoprotection and the role of stress-proteins in natural defenses, autoprotection, and salutogenesis, Medical Hypotheses, 10.1016/S0306-9877(98)90110-4, 51:2, (153-163), Online publication date: 1-Aug-1998. Budinger G, Duranteau J, Chandel N and Schumacker P (1998) Hibernation during Hypoxia in Cardiomyocytes, Journal of Biological Chemistry, 10.1074/jbc.273.6.3320, 273:6, (3320-3326), Online publication date: 1-Feb-1998. Knap J and Harrer J (2019) Medium - Term Results of Coronary Artery Bypass Surgery in Patients with Severe Left Ventricular Dysfunction and Preoperatively Documented Hibernating Myocardium, Acta Medica (Hradec Kralove, Czech Republic), 10.14712/18059694.2019.185, 41:4, (175-179), . Zimmer H (1998) Chapter 3 Adenine nucleotides in cardiac cell injury and restitution Principles of Medical Biology A Multi-Volume Work, Volume 13, 10.1016/S1569-2582(98)80005-6, (83-126), . Eichstädt H (1998) Methods of Nuclear Medicine to Verify Vitality and Efficacy of TMLR TMLR Management of Coronary Artery Diseases, 10.1007/978-3-642-72134-2_4, (47-63), . Schrader J, Decking U and Stumpe T (1998) Recent Advances in Cardiac Adenosine Metabolism Cardiovascular Biology of Purines, 10.1007/978-1-4615-5603-9_19, (312-325), . Wait M and Grayburn P (1997) Effect of preoperative antioxidant supplements on perioperative myocardial injury, The Journal of Thoracic and Cardiovascular Surgery, 10.1016/S0022-5223(97)70034-5, 114:6, (1127-1128), Online publication date: 1-Dec-1997. Tanaka T, Oka Y, Tawara I, Sada T and Kira Y (1997) Effect of time interval between two balloon inflations on ischemic preconditioning during coronary angioplasty, Catheterization and Cardiovascular Diagnosis, 10.1002/(SICI)1097-0304(199711)42:3 3.0.CO;2-A, 42:3, (263-267), Online publication date: 1-Nov-1997. Shishido T, Beppu S, Matsuda H, Yutani C and Miyatake K (1997) Extension of Hemorrhage After Reperfusion of Occluded Coronary Artery: Contrast Echocardiographic Assessment in Dogs, Journal of the American College of Cardiology, 10.1016/S0735-1097(97)00163-0, 30:2, (585-591), Online publication date: 1-Aug-1997. Weil M and Tang W (1997) Cardiopulmonary resuscitation: A promise as yet largely unfilfilled, Disease-a-Month, 10.1016/S0011-5029(97)90026-2, 43:7, (431-501), Online publication date: 1-Jul-1997. Herzog W, Vogel R, Schlossberg M, Edenbaum L, Scott H and Serebruany V (1997) Short-term low dose intracoronary diltiazem administered at the onset of reperfusion reduces myocardial infarct size, International Journal of Cardiology, 10.1016/S0167-5273(96)02883-5, 59:1, (21-27), Online publication date: 1-Mar-1997. Marber M (1997) Viewpoint: stunning and longterm perfusion-contraction matching are clinically indistinguishable components of clinical hibernation and separation, even if practical, is unlikely to matter, Basic Research in Cardiology, 10.1007/BF00797201, 92:S2, (26-29), Online publication date: 1-Mar-1997. Bezstarosti K, Soei L, Verdouw P and Lamers J (1997) Phosphorylation by protein kinase C and the responsiveness of Mg2+-ATPase to Ca2+ of myofibrils isolated from stunned and non-stunned porcine myocardium The Cellular Basis of Cardiovascular Function in Health and Disease, 10.1007/978-1-4615-5765-4_27, (211-218), . Lewis B (1996) Calcium antagonists in patients with left ventriculardysfunction: back on the bridge?, Journal of Cardiac Failure, 10.1016/S1071-9164(96)80086-8, 2, (S259-S265), Online publication date: 1-Dec-1996. Chen R (1996) The Scientific Basis for Hypocalcemic Cardioplegia and Reperfusion in Cardiac Surgery, The Annals of Thoracic Surgery, 10.1016/S0003-4975(96)00462-6, 62:3, (910-914), Online publication date: 1-Aug-1996. Armstrong W (1996) "Hibernating" myocardium: Asleep or part dead?, Journal of the American College of Cardiology, 10.1016/0735-1097(96)00138-6, 28:2, (530-535), Online publication date: 1-Aug-1996. Gazmuri R, Weil M, Bisera J, Tang W, Fukui M and McKee D (1996) Myocardial dysfunction after successful resuscitation from cardiac arrest, Critical Care Medicine, 10.1097/00003246-199606000-00020, 24:6, (992-1000), Online publication date: 1-Jun-1996. Hagerman I, Berglund M, Svedenhag J, Nowak J and Sylvén C (1996) Beat-to-beat QRS amplitude variability after acute myocardial infarction and coronary artery bypass grafting, The American Journal of Cardiology, 10.1016/S0002-9149(96)00030-6, 77:11, (927-931), Online publication date: 1-May-1996. Bezstarosti K, Soei L, Krams R, Ten Cate F, Verdouw P and Lamers J (1996) The effect of a thiadiazinone derived Ca2+ sensitizer on the responsiveness of Mg2+-ATPase to Ca2+ in myofibrils isolated from stunned and nonstunned porcine and human myocardium, Biochemical Pharmacology, 10.1016/0006-2952(96)00083-4, 51:9, (1211-1220), Online publication date: 1-May-1996. Hendel R, Chaudhry F and Bonow R (1996) Myocardial viability, Current Problems in Cardiology, 10.1016/S0146-2806(96)80009-0, 21:3, (147-221), Online publication date: 1-Mar-1996. Schipke J, Korbmacher B, Dorszewski A, Selcan G, Sunderdiek U and Arnold G (1996) Haemodynamic and energetic properties of stunned myocardium in rabbit hearts., Heart, 10.1136/hrt.75.1.55, 75:1, (55-61), Online publication date: 1-Jan-1996. Christian T (1996) Contraction-perfusion matching in reperfused acute myocardial infarction Imaging and Intervention in Cardiology, 10.1007/978-94-009-0115-5_2, (13-27), . Schipke J (1996) Myocardial hibernation New Paradigms of Coronary Artery Disease, 10.1007/978-3-642-53793-6_8, (27-29), . Marban E (1996) Excitation-contraction coupling in hibernating myocardium New Paradigms of Coronary Artery Disease, 10.1007/978-3-642-53793-6_6, (20-23), . Gallagher K (1996) Myocardial hibernation in terms of the flow-function relationship New Paradigms of Coronary Artery Disease, 10.1007/978-3-642-53793-6_4, (13-16), . Leor J and Kloner R (1996) The hibernating myocardium Myocardial Ischemia: Mechanisms, Reperfusion, Protection, 10.1007/978-3-0348-8988-9_27, (453-462), . De Zwaan C, Bär F, Dassen W, Vermeer F and Wellens H (1995) Changes in Wall Motion in Patients Treated for Unstable Angina, Chest, 10.1378/chest.108.4.903, 108:4, (903-911), Online publication date: 1-Oct-1995. Ehring T and Heusch G (1995) Stunned myocardium and the attenuation of stunning by calcium antagonists, The American Journal of Cardiology, 10.1016/S0002-9149(99)80450-0, 75:13, (E61-E67), Online publication date: 1-Apr-1995. Lewis B (1995) Efficacy and safety of nisoldipine coat core in the management of angina pectoris, systemic hypertension, and ischemic ventricular dysfunction, The American Journal of Cardiology, 10.1016/S0002-9149(99)80448-2, 75:13, (E46-E53), Online publication date: 1-Apr-1995. Sheiban I, Tonni S, Marini A and Trevi G (1995) Clinical and therapeutic implications of chronic left ventricular dysfunction in coronary artery disease, The American Journal of Cardiology, 10.1016/S0002-9149(99)80444-5, 75:13, (E23-E30), Online publication date: 1-Apr-1995. Rahimtoola S (1995) From coronary artery disease to heart failure: Role of the hibernating myocardium, The American Journal of Cardiology, 10.1016/S0002-9149(99)80443-3, 75:13, (E16-E22), Online publication date: 1-Apr-1995. Poole-Wilson P (1995) Angiotensin-converting enzyme inhibitors and calcium antagonists after acute myocardial infarction, The American Journal of Cardiology, 10.1016/S0002-9149(99)80441-X, 75:13, (E4-E9), Online publication date: 1-Apr-1995. Jain D and Zaret B (1995) Nuclear Imaging Techniques for the Assessment of Myocardial Viability, Cardiology Clinics, 10.1016/S0733-8651(18)30061-4, 13:1, (43-57), Online publication date: 1-Feb-1995. Lee J (1995) The pathology of cardiac ischaemia: Cellular and molecular aspects, The Journal of Pathology, 10.1002/path.1711750203, 175:2, (167-174), Online publication date: 1-Feb-1995. Schipke J (1995) Myocardial hibernation, Basic Research in Cardiology, 10.1007/BF00795112, 90:1, (26-28), Online publication date: 1-Jan-1995. Marban E (1995) Excitation-contraction coupling in hibernating myocardium, Basic Research in Cardiology, 10.1007/BF00795110, 90:1, (19-22), Online publication date: 1-Jan-1995. Gallagher K (1995) Myocardial hibernation in terms of the flow-function relationship, Basic Research in Cardiology, 10.1007/BF00795108, 90:1, (12-15), Online publication date: 1-Jan-1995. Liedtke A (1995) Mechanical recovery with propionyl-L-carnitine The Carnitine System, 10.1007/978-94-011-0275-9_20, (275-289), . Heusch G and Schulz R (1995) Pathophysiologie des "hibernating" und "stunned" Myokards Interventionen am Herzen, 10.1007/978-3-642-93558-9_30, (367-383), . Baumgart D and Heusch G (1995) Pathophysiologie der Myokardischämie Herz- und kreislaufwirksame Medikamente in Anästhesie, Intensiv- und Notfallmedizin, 10.1007/978-3-642-78777-5_1, (3-45), . Soei L, Sassen L, Fan D, van Veen T, Krams R and Verdouw P (1994) Myofibrillar Ca2+ sensitization predominantly enhances function and mechanical efficiency of stunned myocardium., Circulation, 90:2, (959-969), Online publication date: 1-Aug-1994.Beregi J, Bauters C, McFadden E, Quandalle P, Bertrand M and Lablanche J (1994) Exercise-induced ST-segment depression in patients without restenosis after coronary angioplasty. Relation to preprocedural impaired left ventricular function., Circulation, 90:1, (148-155), Online publication date: 1-Jul-1994. ZUGHAIB M, TANG X, SUN J and BOLLI R (2006) Myocardial Reperfusion Injury: Fact or Myth? A 1993 Appraisal of a Seemingly Endless Controversy a, Annals of the New York Academy of Sciences, 10.1111/j.1749-6632.1994.tb36728.x, 723:1, (218-228), Online publication date: 1-Jun-1994. Sharma H, Verdouw P and Lamers J (1994) Involvement of the sarcoplasmic reticulum calcium pump in myocardial contractile dysfunction: Comparison between chronic pressure-overload and stunning, Cardiovascular Drugs and Therapy, 10.1007/BF00877923, 8:3, (461-468), Online publication date: 1-Jun-1994. Bergmann S, Weinheimer C, Brown M and Perez J (1994) Enhancement of regional myocardial efficiency and persistence of perfusion, oxidative, and functional reserve with paired pacing of stunned myocardium., Circulation, 89:5, (2290-2296), Online publication date: 1-May-1994. Jeroudi M, Hartley C and Bolli R (1994) Myocardial reperfusion injury: Role of oxygen radicals and potential therapy with antioxidants, The American Journal of Cardiology, 10.1016/0002-9149(94)90257-7, 73:6, (B2-B7), Online publication date: 1-Mar-1994. SylvÉN C, Hagerman I, YiÉN M, Nyquist O and Nowak J (1994) Variance ecg detection of coronary artery disease-a comparison with exercise stress test and myocardial scintigraphy, Clinical Cardiology, 10.1002/clc.4960170306, 17:3, (132-140), Online publication date: 1-Mar-1994. Janero D (1994) Myocardial Ischemia–Reperfusion Injury and the Cardioprotective Potential of Natural Antioxidants Natural Antioxidants in Human Health and Disease, 10.1016/B978-0-08-057168-3.50020-5, (411-445), . Korbmacher B, Sunderdiek U, Arnold G, Schulte H and Schipke J (1994) Improved ventricular function by enhancing the Ca++ sensitivity in normal and stunned myocardium of isolated rabbit hearts, Basic Research in Cardiology, 10.1007/BF00794955, 89:6, (549-562), . Finkel M, Oddis C, Hattler B and Simmons R (1994) Myocardial ischemia, stunning and hibernation: blood blow, metabolism and pathophysiology mechanism Myocardial viability, 10.1007/978-94-011-1170-6_2, (5-18), . Ausma J, Ramaekers F, Shivalkar B, Thone F, Flameng W and Borgers M (1994) Cellular Adaptation in Hibernating Myocardium in the Human Cardiac Adaptation and Failure, 10.1007/978-4-431-67014-8_7, (85-99), . Yacoub M (1994) Cardiac Transplantation for Ischaemic Heart Disease Coronary Artery Graft Disease, 10.1007/978-3-642-78637-2_23, (377-389), . Hasebe N, Shen Y and Vatner S (1993) Inhibition of endothelium-derived relaxing factor enhances myocardial stunning in conscious dogs., Circulation, 88:6, (2862-2871), Online publication date: 1-Dec-1993. Benfey B (1993) Functions of myocardial α-adrenoceptors, Journal of Autonomic Pharmacology, 10.1111/j.1474-8673.1993.tb00283.x, 13:5, (351-372), Online publication date: 1-Oct-1993. Nowak J, Yléan M, Hagerman I, Nyquist O and Sylven C (1993) Electrocardiogram signal variance analysis in the diagnosis of coronary artery disease-A comparison with exercise stress test in an angiographically documented high prevalence population, Clinical Cardiology, 10.1002/clc.4960160909, 16:9, (671-682), Online publication date: 1-Sep-1993. Buxton D (1993) Dysfunction in collateral-dependent myocardium. Hibernation or repetitive stunning?, Circulation, 87:5, (1756-1758), Online publication date: 1-May-1993. Nidorf S, Siu S, Galambos G, Weyman A and Picard M (1993) Benefit of late coronary reperfusion on ventricular morphology and function after myocardial infarction, Journal of the American College of Cardiology, 10.1016/0735-1097(93)90101-6, 21:3, (683-691), Online publication date: 1-Mar-1993. Jeremy R and Tonkin A (1993) Detection of jeopardised viable myocardium in patients with coronary artery disease, Medical Journal of Australia, 10.5694/j.1326-5377.1993.tb137525.x, 158:2, (75-76), Online publication date: 1-Jan-1993. Hofmann P, Miller W and Moss R (1993) Altered calcium sensitivity of isometric tension in myocyte-sized preparations of porcine postischemic stunned myocardium., Circulation Research, 72:1, (50-56), Online publication date: 1-Jan-1993. Steenbergen C, Fralix T and Murphy E (1993) Role of increased cytosolic free calcium concentration in myocardial ischemic injury, Basic Research in Cardiology, 10.1007/BF00795412, 88:5, (456-470), . Mallet R and Bünger R (1993) Metabolic Protection of Post-Ischemic Phosphorylation Potential and Ventricular Performance Interactive Phenomena in the Cardiac System, 10.1007/978-1-4615-2946-0_22, (233-241), . Swift P, Turner J, Oxer H, O'Shea J, Lane G and Woollard K (1992) Myocardial hibernation identified by hyperbaric oxygen treatment and echocardiography in postinfarction patients: Comparison with exercise thallium scintigraphy, American Heart Journal, 10.1016/0002-8703(92)90394-B, 124:5, (1151-1158), Online publication date: 1-Nov-1992. Gasser R, Furian C, Grisold M, Dusleag J and Klein W (1992) Myocardial hibernation, The Lancet, 10.1016/0140-6736(92)92344-F, 340:8822, (796-797), Online publication date: 1-Sep-1992. Tubau J and Rahimtoola S (1992) Hibernating myocardium: A historical perspective, Cardiovascular Drugs and Therapy, 10.1007/BF00051149, 6:3, (267-271), Online publication date: 1-Jun-1992. du Toit E and Opie L (1992) Modulation of severity of reperfusion stunning in the isolated rat heart by agents altering calcium flux at onset of reperfusion., Circulation Research, 70:5, (960-967), Online publication date: 1-May-1992.Buxton D, Mody F, Krivokapich J, Phelps M and Schelbert H (1992) Quantitative assessment of prolonged metabolic abnormalities in reperfused canine myocardium., Circulation, 85:5, (1842-1856), Online publication date: 1-May-1992. Boekstegers P, Pfeifer A, Peter W and Werdan K (1992) Contractile Dysfunction of "Reperfused" Neonatal Rat Heart Cells: A Model for Studying "Myocardial Stunning" at the Cellular Level? Oxygen Transport to Tissue XIV, 10.1007/978-1-4615-3428-0_68, (573-582), . Opie L (1992) Postischemic Stunning—The Case for Calcium as the Ultimate Culprit Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion, 10.1007/978-1-4613-1517-9_6, (88-97), . Heusch G and Schulz R (1992) Recruitment of an Inotropic Reserve in Hibernating and Stunned Myocardium Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion, 10.1007/978-1-4613-1517-9_19, (235-250), . Nayler W (1992) Calcium, Calcium Antagonists, Stunning, and Hibernation: An Overview Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion, 10.1007/978-1-4613-1517-9_18, (226-234), . Tubau J and Rahimtoola S (1992) Hibernating Myocardium: A Historical Perspective Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion, 10.1007/978-1-4613-1517-9_15, (192-201), . Przyklenk K and Kloner R (1992) Calcium Antagonists and Stunned Myocardium: Importance for Clinicians? Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion, 10.1007/978-1-4613-1517-9_13, (180-189), . Kloner R and Przyklenk K (1991) Hibernation and Stunning of the Myocardium, New England Journal of Medicine, 10.1056/NEJM199112263252610, 325:26, (1877-1879), Online publication date: 26-Dec-1991. Hedberg P (2016) Congestive heart failure in acute myocardial infarction, Postgraduate Medicine, 10.1080/00325481.1991.11701103, 90:6, (99-113), Online publication date: 1-Nov-1991. Syrota A and Jehenson P (1991) Complementarity of magnetic resonance spectroscopy, positron emission tomography and single photon emission tomography for the in vivo investigation of human cardiac metabolism and neurotransmission, European Journal of Nuclear Medicine, 10.1007/BF02258457, 18:11, (897-923), Online publication date: 1-Nov-1991. Przyklenk K and Kloner R (1991) Calcium antagonists and stunned myocardium: Importance for clinicians?, Cardiovascular Drugs and Therapy, 10.1007/BF00053557, 5:5, (947-951), Online publication date: 1-Oct-1991. Opie L (1991) Postischemic stunning?The case for calcium as the ultimate culprit, Cardiovascular Drugs and Therapy, 10.1007/BF00053550, 5:5, (895-899), Online publication date: 1-Oct-1991. Kloner R and Przyklenk K (1991) Experimental infarct size reduction with calcium channel blockers, Journal of the American College of Cardiology, 10.1016/0735-1097(91)90815-Q, 18:3, (876-878), Online publication date: 1-Sep-1991. Follette D (1991) Penetrating cardic injuries—A look to the future, The Annals of Thoracic Surgery, 10.1016/0003-4975(91)90107-2, 51:5, (701-702), Online publication date: 1-May-1991. Kübler W, Blömer H, Mall G, Siemens I, Zimmermann R, Schömig A, Schanzenbächer P, Lichtlen P, Tillmanns H, Kübler W, Hoberg E, Nordt T, Ott I, Schömig A, Bircks W, Maisch B, Bleifeld W, Terres W, Kreuzer H, Ertl G, Gaudon P, Eilles C and Kochsiek K (1991) Hauptthema: Die ischaemische Herzkrankheit Verhandlungen der Deutschen Gesellschaft für Innere Medizin, 10.1007/978-3-642-84710-3_3, (85-148), . February 1, 1991Vol 83, Issue 2 Advertisement Article InformationMetrics Copyright © 1991 by American Heart Associationhttps://doi.org/10.1161/01.CIR.83.2.681 Originally publishedFebruary 1, 1991 PDF download Advertisement
Referência(s)