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Projections from the upper lumbar cord to the cerebellar nuclei in the rat, studied by anterograde axonal tracing

1999; Wiley; Volume: 412; Issue: 4 Linguagem: Inglês

10.1002/(sici)1096-9861(19991004)412

1096-9861

Matsuo Matsushita,

Neuroscience and Neuropharmacology Research

Journal of Comparative NeurologyVolume 412, Issue 4 p. 633-648 Original Article Projections from the upper lumbar cord to the cerebellar nuclei in the rat, studied by anterograde axonal tracing Matsuo Matsushita, Corresponding Author Matsuo Matsushita mmatsusi@md.tsukuba.ac.jp Department of Anatomy, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Ibaraki 305–8575, JapanKarasuyama 2-530-124, Tsuchiura, Ibaraki 300-0836, Japan.Search for more papers by this author Matsuo Matsushita, Corresponding Author Matsuo Matsushita mmatsusi@md.tsukuba.ac.jp Department of Anatomy, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Ibaraki 305–8575, JapanKarasuyama 2-530-124, Tsuchiura, Ibaraki 300-0836, Japan.Search for more papers by this author First published: 26 August 1999 https://doi.org/10.1002/(SICI)1096-9861(19991004)412:4 3.0.CO;2-QCitations: 23AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract The spinocerebellar tracts arising from the upper lumbar cord consist of the dorsal and the ventral spinocerebellar tracts (DSCT and VSCT), which ascend ipsilaterally and contralaterally, respectively. By using anterograde labeling with biotinylated dextran in the rat, this study examined whether the lumbar DSCT and the VSCT project to the cerebellar nuclei. Injections of the tracer were made unilaterally at levels between the L1 and L3 segments, with diffusion to either a rostral or a caudal segment. The injections resulted in bilateral labeling of axon terminals in the cerebellar nuclei. In the medial nucleus, labeled terminals were distributed in medial, ventral, and ventrolateral parts of the middle subdivision and ventral parts of the caudomedial subdivision. In the anterior interpositus nucleus, they were distributed in medial and dorsomedial parts throughout the rostrocaudal extent. Labeled terminals were seen within the dorsomedial crest region. In the posterior interpositus nucleus, labeled terminals were seen in the rostromedial extension, the caudomedial part, and the caudal pole. Labeled terminals were seen in the hilus and the ventral part of the lateral nucleus. Projections of the DSCT and the VSCT to these regions were confirmed after tracer injections preceded by sectioning of either tract. Both tracts projected bilaterally, but the DSCT projected mainly ipsilaterally. The present study suggests that the spinocerebellar tracts originating from the upper lumbar cord (the lumbar DSCT and the VSCT) project to specific areas of the cerebellar nuclei to transmit information about the peripheral and central events during the movement of hindlimbs. J. Comp. Neurol. 412:633–648, 1999. © 1999 Wiley-Liss, Inc. Citing Literature Volume412, Issue44 October 1999Pages 633-648 RelatedInformation