Artigo Revisado por pares

A gene influencing active avoidance performance in mice

1973; Elsevier BV; Volume: 11; Issue: 4 Linguagem: Inglês

10.1016/0031-9384(73)90036-x

ISSN

1873-507X

Autores

A. Oliverio, Basil E. Eleftheriou, Donald W. Bailey,

Tópico(s)

Plant Molecular Biology Research

Resumo

Active avoidance learning performance, measured in a shuttle box apparatus, differed significantly in C57BL/6By and BALB/cBy mice. Evaluation of this performance in reciprocal F1 hybrids of these two inbred strains, and in their recently developed recominant inbred strains allowed characterization of a single dominant autosomal gene which influences active avoidance performance. Use of congenic lines B6.C-H-25c and B6.C-H(w56) determined linkage of this gene, Aal, on Chromosome 9 (LG II) of the mouse.

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