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Pre-operative homocysteine levels and morbidity and mortality following cardiac surgery

2008; Oxford University Press; Volume: 30; Issue: 8 Linguagem: Inglês

10.1093/eurheartj/ehp015

1522-9645

Marco Ranucci, Andrea Ballotta, Alessandro Frigiola, Alessandra Boncilli, Simonetta Brozzi, Elena Costa, Rajendra H. Mehta,

Cardiac, Anesthesia and Surgical Outcomes

AimsElevated homocysteinaemia is associated not only with an increased risk for cardiovascular disease but also for increased morbidity and mortality in patients with established coronary artery or cerebrovascular disease. Whether elevated homocysteine further increases the morbidity and mortality in patients undergoing cardiac surgery on cardiopulmonary bypass (CPB) (a prothrombotic state itself) remains less known.