Orthogonal Base Pairs Continue to Evolve
2004; Elsevier BV; Volume: 11; Issue: 1 Linguagem: Inglês
10.1016/j.chembiol.2004.01.007
ISSN1879-1301
Autores Tópico(s)Advanced biosensing and bioanalysis techniques
ResumoRecent developments in the design and construction of unusual analogs of the natural nucleic acid bases have reached a milestone with the report (in this issue of Chemistry & Biology [1Kimoto M. Endo M. Mitsui T. Okuni T. Hirao I. Yokoyama S. Chem. Biol. 2004; 11 (, this issue): 47-55Abstract Full Text Full Text PDF PubMed Scopus (56) Google Scholar]) of a new orthogonal base pair that allows site-specific introduction of a photo-crosslinkable modified base into an RNA molecule by T7 RNA polymerase-mediated transcription of DNA containing the base-pairing partner.
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