Simple and rapid voltammetric determination of morphine at electrochemically pretreated glassy carbon electrodes
2009; Elsevier BV; Volume: 79; Issue: 3 Linguagem: Inglês
10.1016/j.talanta.2009.05.011
ISSN1873-3573
AutoresFei Li, Jixia Song, Gao Dongmei, Qixian Zhang, Dongxue Han, Li Niu,
Tópico(s)Analytical chemistry methods development
ResumoA simple and rapid method for morphine detection has been described based on electrochemical pretreatment of glassy carbon electrode (GCE) which was treated by anodic oxidation at 1.75 V, following potential cycling in the potential range from 0 V to 1.0 V vs. Ag|AgCl reference electrode. The sensitivity for morphine detection was improved greatly and the detection limit was 0.2 μM. The reproducibility of the voltammetric measurements was usually less than 3% RSD for six replicate measurements. Moreover, this method could readily discriminate morphine from codeine. And an electrochemical detection of morphine in spiked urine sample was succeeded with satisfactory results.
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