PREVALENCE OF AND MORTALITY FROM HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 IN BISSAU, WEST AFRICA
1989; Elsevier BV; Volume: 333; Issue: 8642 Linguagem: Inglês
10.1016/s0140-6736(89)92281-2
ISSN1474-547X
AutoresAnja Poulsen, Peter Aaby, Kirsten Frederiksen, Birgit Kvinesdal, Kåre Mølbak, Francisco Dias, Edgar Lauritzen,
Tópico(s)HIV, Drug Use, Sexual Risk
ResumoIn a community based prevalence study of HIV infection in Bissau, West Africa, 1987, the population in 100 randomly selected "houses" was asked to participate. 89% (1329/1499) were examined and had a blood sample taken. None was HIV-1 seropositive but 4.7% were seropositive for HIV-2 (0.6% in children, 8.9% in those aged 15 years and over, and 20% in those aged 40 years and over). There was no significant difference in seroprevalence between areas or ethnic groups or between individuals of different civil status when age was taken into account. Sexual contact and blood transfusions were the dominant transmission routes, and no case of vertical transmission was identified. The HIV-2 seroprevalence in spouses of HIV-2 seropositive index persons was 40%. For a history of blood transfusion the relative risk of being HIV-2 seropositive was 103.6 in children and 2.4 for adults. After exclusion of spouses, no clustering of HIV-2 seropositivity was seen. At follow-up, after a mean observation time of 325 days, there was an excess mortality for HIV-2 seropositives. The relative risk of dying for HIV-2 seropositive children was 60.8 and for adults 5.0.
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