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Macrocarpals H, I, and J from the Leaves of Eucalyptus globulus

1996; American Chemical Society; Volume: 59; Issue: 9 Linguagem: Inglês

10.1021/np9604994

1520-6025

Kenji Osawa, Hideyuki Yasuda, Hiroshi Morita, Koichi Takeya, Hideji Itokawa,

Food Chemistry and Fat Analysis

A 50% EtOH extract of Eucalyptus globulus leaves yielded eight phloroglucinol--sesquiterpene-coupled constituents, including three novel compounds named macrocarpals, H, I, and J. Some of these compounds possessed antibacterial activity against oral pathogenic microorganisms with MIC values ranging from 0.20 micrograms/mL to 6.25 micrograms/mL. Inhibition of glucosyltransferase activity by these compounds was also noted.