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Thrombocytopenia in Plasmodium vivax Malaria: How Significant?

2014; Hindawi Publishing Corporation; Volume: 2014; Linguagem: Inglês

10.1155/2014/567469

1687-9694

Arti Muley, Jitendra D. Lakhani, Saurabh Bhirud, Abhinam Patel,

Venomous Animal Envenomation and Studies

Introduction . Thrombocytopenia is frequently noticed with P. falciparum malaria but is less reported and studied with P. vivax . Materials and Methods . The study was conducted in the Department of Medicine, SBKS MI & RC, Pipariya. We included patients who were diagnosed with vivax malaria. The data regarding their clinical and hematological profile was collected and analysed. Result . A total of 66 patients were included. 42 (63%) had platelet count <100000/mm 3 . Mean platelet count was 1,18,650, range being 8000/mm 3 –6,10,000/mm 3 . Amongst those with thrombocytopenia, 16 (38.09%) had anemia, 14 (33.33%) had serum creatinine >1.2 gm/dL, 15 (35.71%) had jaundice (s. bilirubin > 1.2), 2 (4.76%) had altered sensorium, 6 (14.28%) had ARDS, 2 needed ventilator support, and 1 expired. Amongst those with normal platelet count, 5 (20.83%) had anemia and 1 had jaundice whereas none had elevated s. creatinine, altered sensorium, or lung involvement. Conclusion . Thrombocytopenia is now being seen more commonly with vivax malaria. Patients with platelet count <1 lac/cumm have more severe disease.