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Synthesis of vinca alkaloids and related compounds XLVIII synthesis of (+)-catharanthine and (±)-allocatharanthine

1990; Elsevier BV; Volume: 46; Issue: 5 Linguagem: Inglês

10.1016/s0040-4020(01)81977-3

1464-5416

Csaba Szántay, Hedvig Bölcskei, Eszter Gács‐Baitz,

Plant Parasitism and Resistance

The first synthesis of natural (+)-catharanthine (ulbar>1) has been achieved in a few steps and in ∼20 % overall yield based on indole-3--acetic acid. The isomeric (±)-allocatharanthine was also prepared.