Immobilization of Bis(Bipyridine) BINOL Ligands and Their Use in Chiral Resolution
2009; American Chemical Society; Volume: 11; Issue: 21 Linguagem: Inglês
10.1021/ol901958v
ISSN1523-7060
AutoresJens Bunzen, U. Kiehne, C. Benkhauser-Schunk, Arne Lützen,
Tópico(s)Axial and Atropisomeric Chirality Synthesis
ResumoAn enantiomerically pure bis(bipyridine) BINOL ligand was synthesized which was functionalized with an iodine substituent in its periphery. Using this halogen function, the ligand was immobilized on a commercially available polystyrene gel via Suzuki cross-coupling. The functionalized gel was found to be effective in the chiral resolution of similar bis(bipyridine) ligands based on a Tröger's base core.
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