Persistent Salmonella Infection in a Female Carrier for Chronic Granulomatous Disease
1970; American College of Physicians; Volume: 73; Issue: 4 Linguagem: Inglês
10.7326/0003-4819-73-4-595
ISSN1539-3704
Autores Tópico(s)Trace Elements in Health
ResumoA female carrier for chronic granulomatous disease of childhood has had persistent systemic infections with Salmonella enteritidis for more than 3 years despite rigorous medical and surgical attempts to eradicate the sepsis. Unusual susceptibility to bacterial infection has not previously been described in carriers of chronic granulomatous disease of childhood, and it is postulated that this patient's persistent infection is due to survival of salmonellae in the macrophages of her reticuloendothelial system, where they are protected from the effects of systemic antibiotics.
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