Progeria in siblings: A rare case report
2011; Medknow; Volume: 56; Issue: 5 Linguagem: Inglês
10.4103/0019-5154.87162
ISSN1998-3611
AutoresR Sowmiya, D Prabhavathy, Sivasankar Jayakumar,
Tópico(s)RNA modifications and cancer
ResumoProgeria, also known as Hutchinson-Gilford syndrome, is an extremely rare, severe genetic condition wherein symptoms resembling aspects of aging are manifested at an early age. It is an autosomal dominant disorder. It is not seen in siblings of affected children although there are very few case reports of progeria affecting more than one child in a family. Here we are presenting two siblings, a 14-year-old male and a 13-year-old female with features of progeria, suggesting a possible autosomal recessive inheritance.
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