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Hypercalciuria and Hypercalcemia Complicating Immobilization

1978; American Medical Association; Volume: 132; Issue: 6 Linguagem: Inglês

10.1001/archpedi.1978.02120310017001

1538-3628

William H. Bergstrom,

Injury Epidemiology and Prevention

In this issue of theJournal(132:560-564, 1978), Rosen and his colleagues reemphasize a phenomenon long known but often forgotten, the dissolution of bone that results from immoblization. They described six boys, between 4 and 16 years old, in whom hypercalcemia and hypercalciuria occurred after bed rest and cast application for fracture of dislocation of weight-bearing bones. Others have found hypercalciuria, with or without hypercalcemia, in association with paralysis, 1 severe burns, 2 extensive casting for conditions other than fracture, 3 the weightless state enjoyed (or at least endured) by astronauts, 4 and voluntary bed rest, with 5 or without, body spicas. 6 In some of these studies, decreased bone density was evident by radiography 1 or by gamma scanning 6 ; early and extensive osteoporosis characterized the large series of burn patients described by Evans and Smith. 7 Although most subjects have been adults, the few reports involving children suggest that