Differential Diagnosis of Solitary Pulmonary Nodules with Positron Emission Tomography Using [11C]L-Methionine
1988; Lippincott Williams & Wilkins; Volume: 12; Issue: 5 Linguagem: Inglês
10.1097/00004728-198809010-00015
ISSN1532-3145
AutoresKazuo Kubota, T Matsuzawa, Takehiko Fujiwara, Yoshinao Abe, Masatoshi Ito, Jun Hatazawa, Tatsuo Ido, Kiichi Ishiwata, Seiichi Watanuki,
Tópico(s)Chemical Reactions and Isotopes
ResumoTwo patients with solitary pulmonary nodules, 1.5–2.0 cm in diameter, were studied by positron emission tomography using [11C-Methyl]L-methionine (11C-Met). Case 1 showed high accumulation of 11C-Met in the tumor, and a tumor/muscle ratio of 6.0 suggesting malignancy. Tissue obtained by biopsy revealed a squamous cell carcinoma. Case 2 showed nonspecific isotope accumulation in the tumor, and a tumor/muscle ratio of 1.2 suggesting a benign lesion. Lung biopsy demonstrated granuloma. Positron emission tomography with 11C-Met seems to be useful for the differential diagnosis of solitary lung nodules.
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