Propranolol in the treatment of neuroleptic-induced akathisia
1984; American Psychiatric Association; Volume: 141; Issue: 3 Linguagem: Inglês
10.1176/ajp.141.3.412
ISSN1535-7228
AutoresJ F Lipinski, George S. Zubenko, B.M. Cohen, Paul Barreira,
Tópico(s)Schizophrenia research and treatment
ResumoBack to table of contents Previous article Next article No AccessPropranolol in the treatment of neuroleptic-induced akathisiaPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.141.3.412AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractFourteen patients with neuroleptic-induced akathisia were treated with propranolol in an open trial. All patients demonstrated substantial improvement of their akathisia; nine of the 14 obtained complete remission. Response was quite rapid, occurring within 24 hours in most cases. Doses required for improvement were low (30-80 mg/day), and side effects were few. Lithium-induced tremor improved considerably, but symptoms of parkinsonism and tardive dyskinesia showed little change. Preliminary results with certain other beta blockers suggest that they are less effective than propranolol in the treatment of akathisia. 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