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Unilateral Keratosis Follicularis

1977; American Medical Association; Volume: 113; Issue: 10 Linguagem: Inglês

10.1001/archderm.1977.01640100137039

1538-3652

Steven A. Binnick,

Hedgehog Signaling Pathway Studies

To the Editor.— Keratosis follicularis (Darier's disease) usually presents as a symmetrical eruption of keratotic, often greasy, follicular and perifollicular papules. Sites of predilection are the chest, upper back, extremities, scalp, and inguinal area. It is thought to be transmitted as an autosomal dominant with incomplete penetrance. We report a case of an unusual variant of Darier's disease. Report of a Case.— An 18-year-old man came to us with a mildly pruritic, papular eruption that involved the right side of the back, the right anterior chest, and the right axilla and that was of six months' duration. He stated that all of the lesions appeared during the first month of involvement and subsequently the eruption remained stable. Betamethasone cream had relieved the pruritus, though without visible effect on the lesions. He was in good health and denied any trauma preceding the onset. Family history was negative. Examination of the skin