Isolation of a Novel Aggregatibacter actinomycetemcomitans Serotype b Bacteriophage Capable of Lysing Bacteria within a Biofilm
2011; American Society for Microbiology; Volume: 77; Issue: 9 Linguagem: Inglês
10.1128/aem.02115-10
ISSN1098-5336
AutoresMario Castillo‐Ruiz, Enrique D. Vinés, Camilo Montt, Jorge Onrubia Fernández, José Manuel Delgado, Juan Carlos Hormazábal, Mauricio Bittner,
Tópico(s)Microbial infections and disease research
ResumoA bacteriophage specific for Aggregatibacter actinomycetemcomitans serotype b, able to kill the bacterium within a biofilm, was isolated. Random mutagenesis of this phage rendered a bacteriophage able to kill 99% of the bacteria within a biofilm. This is the first report of a biocontrol experiment against A. actinomycetemcomitans.
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