Artigo Revisado por pares

Contragestion and Other Clinical Applications of RU 486, an Antiprogesterone at the Receptor

1989; American Association for the Advancement of Science; Volume: 245; Issue: 4924 Linguagem: Inglês

10.1126/science.2781282

ISSN

1095-9203

Autores

Étienne-Émile Baulieu,

Tópico(s)

Hormonal Regulation and Hypertension

Resumo

RU 486, a steroid with high affinity for the progesterone receptor, is the first available active antiprogesterone. It has been used successfully as a medical alternative for early pregnancy interruption, and it also has other potential applications in medicine and for biochemical and pathophysiological endocrine research.

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