Selectfluor™ reagent F-TEDA-BF4 in action: tamed fluorine at your service
1998; Elsevier BV; Volume: 87; Issue: 1 Linguagem: Inglês
10.1016/s0022-1139(97)00127-9
ISSN1873-3328
Autores Tópico(s)Chemical Synthesis and Reactions
ResumoThis paper concerns the discovery, properties and applications in organic synthesis of 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo [2.2.2]octane bis(tetrafluoroborate) (so-called F-TEDA-BF4), one of the best general-purpose user-friendly site-selective electrophilic fluorinating agents to have emerged from a vigorous search worldwide since 1980 for more generally acceptable (non-gaseous, less aggressive, non-explosive, less toxic, relatively inexpensive) reagents than perchloryl fluoride, O-F compounds like trifluoromethyl hypofluorite or caesium fluoroxysulfate, xenon difluoride or fluorine itself. The information presented is based on literature available prior to January 1997.
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