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Neuroradiologic Screening in Normal-Pressure Glaucoma: Study Results and Literature Review

2002; Lippincott Williams & Wilkins; Volume: 11; Issue: 4 Linguagem: Inglês

10.1097/00061198-200208000-00002

1536-481X

Iqbal Ike K. Ahmed, Fred Feldman, Walter Kucharczyk, Graham E. Trope,

Retinal and Macular Surgery

Purpose To determine if there was an increased prevalence of intracranial compressive lesions in patients with clinically diagnosed normal-pressure glaucoma compared with a group of patients with progressive primary open-angle glaucoma. Patients and Methods In a prospective, comparative, observational case series, the authors performed cranial magnetic resonance imaging in patients with consecutively diagnosed normal-pressure glaucoma (n = 62) and progressive primary open-angle glaucoma with controlled intraocular pressures (n = 70). The prevalence of intracranial compressive lesions, demographic data, and clinical characteristics were compared between both groups. Results Four of the 62 (6.5%) patients with normal-pressure glaucoma had clinically relevant intracranial compressive lesions involving the anterior visual pathway, compared with none of the 70 patients with primary open-angle glaucoma (P = 0.039). Conclusions Intracranial compressive lesions are an important diagnostic consideration in the workup of normal-pressure glaucoma.