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Pitfalls in frozen section diagnosis of malignant melanoma

1983; Wiley; Volume: 51; Issue: 6 Linguagem: Inglês

10.1002/1097-0142(19830315)51

1097-0142

Raphael Shafir, Jehuda Hiss, Haggai Tsur, José Bubis,

Optical Coherence Tomography Applications

CancerVolume 51, Issue 6 p. 1168-1170 ArticleFree Access Pitfalls in frozen section diagnosis of malignant melanoma R. Shafir MD, Corresponding Author R. Shafir MD Department of Plastic Surgery and Pathology, Affiliated with the Tel Aviv University, Sackler School of Medicine, Tel Aviv, Israelc/o Leo Bornstein, FND, Medical Library, Sheba Medical Center, Ramat Gan, Israel===Search for more papers by this authorJ. Hiss MD, J. Hiss MD Chaim Sheba Medical Center, Affiliated with the Tel Aviv University, Sackler School of Medicine, Tel Aviv, IsraelSearch for more papers by this authorH. Tsur MD, H. Tsur MD Department of Plastic Surgery and Pathology, Affiliated with the Tel Aviv University, Sackler School of Medicine, Tel Aviv, IsraelSearch for more papers by this authorJ. J. Bubis MD, J. J. Bubis MD Chaim Sheba Medical Center, Affiliated with the Tel Aviv University, Sackler School of Medicine, Tel Aviv, IsraelSearch for more papers by this author R. Shafir MD, Corresponding Author R. Shafir MD Department of Plastic Surgery and Pathology, Affiliated with the Tel Aviv University, Sackler School of Medicine, Tel Aviv, Israelc/o Leo Bornstein, FND, Medical Library, Sheba Medical Center, Ramat Gan, Israel===Search for more papers by this authorJ. Hiss MD, J. Hiss MD Chaim Sheba Medical Center, Affiliated with the Tel Aviv University, Sackler School of Medicine, Tel Aviv, IsraelSearch for more papers by this authorH. Tsur MD, H. Tsur MD Department of Plastic Surgery and Pathology, Affiliated with the Tel Aviv University, Sackler School of Medicine, Tel Aviv, IsraelSearch for more papers by this authorJ. J. Bubis MD, J. J. Bubis MD Chaim Sheba Medical Center, Affiliated with the Tel Aviv University, Sackler School of Medicine, Tel Aviv, IsraelSearch for more papers by this author First published: 15 March 1983 https://doi.org/10.1002/1097-0142(19830315)51:6 3.0.CO;2-PCitations: 50AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract The importance of obtaining an intraoperative diagnosis and measurement of thickness of a malignant melanoma has emerged since the change in the surgical approach towards thin melanomas (0.75 mm). In experienced centers, both diagnosis and thickness, can be established on frozen section. Eighty-four pigmented lesions were examined on frozen section. Thirty of 31 were correctly diagnosed as malignant melanomas. The one not diagnosed was a regressing melanoma. The frozen section diagnosis of a regressing melanoma is difficult, and this should be deferred until paraffin sections are examined. In 29 consecutive skin melanomas thickness was measured on frozen section and was found to be 0.1–0.4 mm more than that measured on paraffin sections of the same specimens. It is therefore suggested that tumors measuring up to 0.85 mm on frozen section should be included in the group of thin melanoma. Citing Literature Volume51, Issue615 March 1983Pages 1168-1170 ReferencesRelatedInformation