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A new anatomic variant of the aorta: A case report

2008; Elsevier BV; Volume: 48; Issue: 1 Linguagem: Inglês

10.1016/j.jvs.2008.02.026

1097-6809

Eric Hager, Gerald A. Isenberg, Carin F. Gonsalves, Neil Moudgill, Steve Dong, Paul DiMuzio,

Vascular anomalies and interventions

Anatomic anomalies of the infrarenal aorta and iliac arteries are rare. We report a 39-year-old man who presented with an ileo-cecal fistula secondary to Crohn disease. A computed tomography scan and subsequent arteriography noted his aorta bifurcated immediately inferior to the main renal arteries, at the level of the second lumbar vertebrae. Associated vascular anomalies included a common superior mesenteric artery/celiac axis plus multiple renal arteries. To our knowledge, this is the first report of this aortic anomaly in the literature. Anatomic anomalies of the infrarenal aorta and iliac arteries are rare. We report a 39-year-old man who presented with an ileo-cecal fistula secondary to Crohn disease. A computed tomography scan and subsequent arteriography noted his aorta bifurcated immediately inferior to the main renal arteries, at the level of the second lumbar vertebrae. Associated vascular anomalies included a common superior mesenteric artery/celiac axis plus multiple renal arteries. To our knowledge, this is the first report of this aortic anomaly in the literature. Anomalies of the aortoiliac arteries are exceedingly rare, with few case reports in the literature.1Oduro G.D. Cope L.H. Rogers I.M. Case report: lower limb arterial blood supply arising from the renal artery with congenital absence of the ipsilateral iliac arteries.Clin Radiol. 1992; 45: 215-217Abstract Full Text PDF PubMed Scopus (9) Google Scholar, 2Koyama T. Kawada T. Kitanaka Y. Katagiri K. Ohno M. Ikeshita M. et al.Congenital anomaly of the external iliac artery: a case report.J Vasc Surg. 2003; 37: 683-685Abstract Full Text Full Text PDF PubMed Scopus (24) Google Scholar, 3Greeb J. Congenital anomalies of the iliofemoral artery.J Cardiovasc Surg. 1977; 18: 317-323PubMed Google Scholar, 4Tamisier D. Melki J.P. Cormier J.M. Congenital anomalies of the external iliac artery: case report and review of the literature.Ann Vasc Surg. 1990; 4: 510-514Abstract Full Text PDF PubMed Scopus (25) Google Scholar Most vascular variations are asymptomatic and noted incidentally upon imaging for other medical concerns; when detected, however, further arterial imaging may be important for patient care. The current imaging modalities of choice include conventional arteriography and computed tomography angiography (CTA) with three-dimensional reconstruction. We present a congenital vascular anomaly wherein the aortic bifurcation arises just inferior to normally located main renal arteries, with a dominant left common iliac artery giving rise to the inferior mesenteric artery as well as the paired lumbar arteries. To our knowledge, this anomaly has not been previously reported. A 39-year-old man presented with right flank pain, nausea, and emesis for 2 weeks. He had no significant past medical or surgical history, and his family history was unremarkable. A nonpulsatile, tender mass was noted on examination of his right lower quadrant. He had normal upper and lower extremity pulses without evidence of a peripheral aneurysm. A CT scan revealed an inflammatory mass at the terminal ileum with creeping fat consistent with Crohn disease. Coincidentally, his aortic bifurcation occurred immediately distal to the main renal arteries, at the level of the second lumbar vertebra (Fig 1, a). The right common iliac artery traveled in a circuitous route through the right retroperitoneum (Fig 1, c) and ultimately bifurcated at the level of the superior acetabular rim (Fig 1, f). The left common iliac artery coursed straight into the pelvis, bifurcating high at the fifth lumbar vertebra (Fig 1, e). Associated findings on this scan included the inflammatory mass (Fig 1, d) and a malrotated left kidney (Fig 1, b). He received outpatient treatment for the Crohn disease; however, the symptoms returned 6 weeks later. A CT scan revealed an abscess with a fistula at the terminal ileum, indicating the need for right hemicolectomy. Because the right common iliac artery coursed within the planned operative field, an arteriogram was performed to characterize further the aberrancy (Fig 2). In addition to the nonbranching right iliac artery (Fig 3, a) and high bifurcation of the aorta, additional views noted:1a common celiac axis-superior mesenteric artery trunk (Fig 3, b);2paired lumbar arteries off the dominant left iliac artery (Fig 3, b) and a replaced right hepatic artery;3four left renal arteries and three right renal arteries;4the medial sacral artery branching off the left proximal common iliac 1 cm proximal to the left renal artery; and5the low right iliac bifurcation at the acetabular rim and the high left iliac bifurcation at the level of the fifth lumbar vertebra (Fig 3, c).Fig 3Selective arteriograms show (a) circuitous route of the right common iliac artery with no branches, (b) common superior mesenteric/celiac trunk and paired lumbar arteries, and (c) bifurcation points of the left and right iliac arteries as well as the femoral bifurcations.View Large Image Figure ViewerDownload Hi-res image Download (PPT) An uncomplicated right hemicolectomy was performed to remove the nonperforated inflammatory mass. The right common iliac artery coursed within the right retroperitoneum but was not involved in the inflammatory process and did not require mobilization. The patient recovered from surgery without vascular complications. The patient described exhibits numerous variants of arterial anatomy. Most unusual is the iliac bifurcation located at the second lumbar vertebrae with a circuitous retroperitoneal course of the right common iliac artery. In conjunction with a common celiac-superior mesenteric arterial trunk, supernumerary renal arteries, and dominance of the left common iliac artery, the patient demonstrates truly unique anatomy. Understanding of the normal embryologic development of the abdominal aorta lends light in understanding this anomaly. In the embryo, development of the aorta begins in the third gestational week with the dorsal migration of two lines of cells from the endocardial mesenchyme. These cells grow along the neural groove, eventually fusing into a single aorta. Numerous segmental arteries form and regress, with the 10th, 13th, and 22nd persisting to form the celiac, superior mesenteric, and inferior mesenteric arteries, respectively. The common iliac arteries form by way of anastomoses between the allantoic and fifth lumbar dorsal intersegmental arteries. The umbilical artery gives rise to the internal iliac artery, and the external iliac artery forms from a bud from the common iliac artery.5Lin P. Chaikof E. Embryology, anatomy and surgical exposure of the great abdominal vessels.Surg Clin North Am. 2000; 80 (xiv): 417-433Abstract Full Text Full Text PDF PubMed Scopus (56) Google Scholar In this patient, we hypothesize that a partial interruption of the normal fusion between the dorsal aorta gave rise to a dominant left common iliac artery and with it, the origin of the inferior mesenteric and paired lumbar arteries. The natural history of this variation is unknown; however, correlation between this and a replaced right subclavian artery suggests that aneurysm formation might be observed.6Austin E.H. Wolfe W.G. Aneurysm of aberrant subclavian artery with a review of the literature.J Vasc Surg. 1985; 2 ([review]): 571-577PubMed Scopus (176) Google Scholar As such, follow-up imaging may be important for early detection of potential aneurysmal disease. Although this variant is unique, the literature describes known variations of iliac anatomy, with a reported incidence of 6 in 8000 patients.3Greeb J. Congenital anomalies of the iliofemoral artery.J Cardiovasc Surg. 1977; 18: 317-323PubMed Google Scholar Tamisier et al4Tamisier D. Melki J.P. Cormier J.M. Congenital anomalies of the external iliac artery: case report and review of the literature.Ann Vasc Surg. 1990; 4: 510-514Abstract Full Text PDF PubMed Scopus (25) Google Scholar classified these variants into three major categories: group 1 are anomalies of origin or course, group 2 are hypoplasia or atresia with a persistent sciatic artery, and group 3 are isolated hypoplasia or atresia. Group 1 variants are usually asymptomatic and coincidentally found. Group 2 have a high incidence of aneurysm formation, typically presenting with acute occlusion or embolism. Most published case reports involve this classification.7Williams L.R. Flanigan D.P. O'Connor R.J. Schuler J.J. Persistent sciatic artery: clinical aspects and operative management.Am J Surg. 1983; 145: 687-693Abstract Full Text PDF PubMed Scopus (64) Google Scholar, 8Martin K.W. Hyde G.L. McCready R.A. Hull D.A. Sciatic artery aneurysms: report of three cases and review of literature.J Vasc Surg. 1986; 4: 365-371PubMed Scopus (53) Google Scholar, 9McLellan G.L. Morettin L.B. Persistent sciatic artery: clinical, surgical and angiographic aspects.Arch Surg. 1982; 117: 812-822Crossref Scopus (45) Google Scholar Group 3 often presents with claudication, typically in the second through fifth decades of life, and may necessitate surgical intervention.4Tamisier D. Melki J.P. Cormier J.M. Congenital anomalies of the external iliac artery: case report and review of the literature.Ann Vasc Surg. 1990; 4: 510-514Abstract Full Text PDF PubMed Scopus (25) Google Scholar, 10Howard J.M. Goudelock W.J. Couves C.M. Congenital atresia of the external iliac artery.Arch Surg. 1957; 75: 296-299Crossref Scopus (10) Google Scholar Humans may exhibit other abdominal aortic branch anomalies, with most aberrancy involving the celiac axis and mesenteric arteries. A study by Koops et al11Koops A. Wojciechowski B. Broering D. Adams G. Krupski-Berdein G. Anatomic variations of the Hepatic Arteries in 604 selective celiac and superior mesenteric Angiographies.Surg and Radiol Anat. 2004; 26: 239-244Crossref PubMed Scopus (175) Google Scholar examined 604 patients who underwent celiac and superior mesenteric angiography and found aberrancy in 21% of patients. The most common variant cited was a replaced right hepatic artery arising from the superior mesenteric artery in 12% rather than the celiac axis, followed by a replaced left hepatic artery emanating from the left gastric artery in 3%. Celiac axis anatomy variants existed in 4% of patients, along with a combination of these variants in 2%. These anomalies, however, are exceedingly rare in conjunction with iliac anatomic variation and were not noted in any of the 604 patients.11Koops A. Wojciechowski B. Broering D. Adams G. Krupski-Berdein G. Anatomic variations of the Hepatic Arteries in 604 selective celiac and superior mesenteric Angiographies.Surg and Radiol Anat. 2004; 26: 239-244Crossref PubMed Scopus (175) Google Scholar This case demonstrates a common origin of these arteries. Herein we have described a unique variant of aortic anatomy, one that has not been described to our knowledge in the literature. Associated vascular findings included multiple bilateral renal arteries and a common celiac-mesenteric trunk. Although it was discovered upon investigation of right retroperitoneal pathology, we do not believe the inflammatory process had any bearing on the patient's noted vascular anatomy. Long-term follow-up is suggested given the possibility of aneurysmal degeneration.