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An approach for understanding the inflammation and cancer relationship

2009; Elsevier BV; Volume: 126; Issue: 1-2 Linguagem: Inglês

10.1016/j.imlet.2009.08.006

1879-0542

Susan Costantini, Francesca Capone, Eliana Guerriero, Giuseppe Castello,

Cancer Immunotherapy and Biomarkers

It is well known that persistent inflammatory conditions can induce the cancer formation. In fact, cytokines and chemokines play a crucial role in the promoting of angiogenesis, metastasis, and subversion of adaptive immunity. These proteins are involved in cancer-related inflammation and can represent a target for innovative diagnostic and therapeutic strategies useful to clinical studies.