Produção Nacional
Neurodevelopment of Amazonian Infants: Antenatal and Postnatal Exposure to Methyl- and Ethylmercury
2012; Hindawi Publishing Corporation; Volume: 2012; Linguagem: Inglês
10.1155/2012/132876
ISSN1110-7251
AutoresJosé G. Dórea, Rejane C. Marques, Cintya Isejima,
Tópico(s)Marine animal studies overview
ResumoNeurodevelopment as Gesell development scores (GDSs) in relation to mercury exposure in infants (<6 months of age) of one urban center and two rural villages, respectively, of fisherman and cassiterite miners. Mean total hair-Hg (HHg) concentrations of infants from Itapuã ( 3.95 ± 1.8 ppm) were statistically ( P = 0.0001 ) different from those of infants from Porto Velho ( 3.84 ± 5.5 ppm) and Bom Futuro ( 1.85 ± 0.9 ppm). Differences in vaccine coverage among these populations resulted in significantly higher ( P = 0.0001 ) mean ethylmercury (EtHg) exposure in urban infants (150 μg) than in infants from either village (41.67 μg, Itapuã; 42.39 μg, Bom Futuro). There was an inverse significant (Spearman r = − 0.2300 ; P = 0.0376 ) correlation between HHg and GDS for infants from Porto Velho, but not for the rural infants from Bom Futuro (Spearman r = 0.1336 ; P = 0.0862 ) and Itapuã (Spearman r = 0.1666 ; P = 0.5182 ). Logistic regression applied to variables above or below the median GDS showed that EtHg exposure (estimated probability = − 0.0157 ; P = 0.0070 ) and breastfeeding score (estimated probability = − 0.0066 ; P = 0.0536 ) score were significantly associated with GDS. Conclusion . In nurslings whose mothers are exposed to different levels of fish-MeHg (HHg), a higher score of neurological development at six months was negatively associated with exposure to additional TCV-EtHg. Results should be interpreted with caution because of unaccounted variables.
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