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Measurement of Molecular Orientation in a Subcellular Compartment by Synchrotron Infrared Spectromicroscopy

2008; Wiley; Volume: 9; Issue: 10 Linguagem: Inglês

10.1002/cphc.200800211

1439-7641

Luca Quaroni, Theodora Zlateva, Diana E. Bedolla, Sebastiano Massaro, Vincent Torre,

Protein Structure and Dynamics

Subcellular dichroism at the diffraction limit: Synchrotron infrared spectromicroscopy provides a snapshot of the axial molecular architecture in the outer segment of an intact retinal rod cell (see picture), which reinforces the role of this technique as a tool for in vivo studies of biomolecular structure–function relationships.