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Safety and effectiveness of Niaspan when added sequentially to a statin for treatment of dyslipidemia

2001; Elsevier BV; Volume: 87; Issue: 4 Linguagem: Inglês

10.1016/s0002-9149(00)01410-7

1879-1913

Megan L. Wolfe, Sara F. Vartanian, Joyce L. Ross, Lori-Lynn Bansavich, Emile R. Mohler, Emma A. Meagher, Christopher A. Friedrich, Daniel J. Rader,

Pharmaceutical Practices and Patient Outcomes

Niaspan, when added to a stable dose of a statin in 66 subjects, was found to be safe and highly effective in improving lipid parameters. Subgroup analyses demonstrated its effectiveness in lowering low-density lipoprotein cholesterol in persons not at the National Cholesterol and Education Program low-density lipoprotein cholesterol target and in raising high-density lipoprotein cholesterol in persons with levels < 40 mg/dl.