Artigo Revisado por pares

Electrochemical assay of superoxide based on biomimetic enzyme at highly conductive TiO2 nanoneedles: from principle to applications in living cells

2009; Royal Society of Chemistry; Issue: 21 Linguagem: Inglês

10.1039/b902150g

ISSN

1364-548X

Autores

Yongping Luo, Yang Tian, Rui Qi,

Tópico(s)

Conducting polymers and applications

Resumo

A novel strategy for extremely durable, reliable, and selective in situ real-time determination of superoxide anion (O2˙−) based on direct electron transfer of a biomimeticsuperoxide dismutase (SOD), Mn3(PO4)2, at highly conductive TiO2 nanoneedles is reported for the first time, and is further exploited for the determination of O2˙− from living normal and cancer ovary cells directly adhered onto the modified surface, suggesting that O2˙− might be proposed as a biomarker of cancer.

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