Disposition of intra-articularly injected cortisone and hydrocortisone
1959; Wiley; Volume: 2; Issue: 5 Linguagem: Inglês
10.1002/1529-0131(195910)2
ISSN1529-0131
AutoresRalph E. Peterson, Roger L. Black, Joseph J. Bunim,
Tópico(s)Adrenal Hormones and Disorders
ResumoCortisone and hydrocortisone labeled with C14 were found to disappear from the synovial cavity rapidly and at the same rate when injected intra-articularly. Only a small portion of injected steroid was metabolized locally. Transformation of cortisone to hydrocortisone by synovial tissue was not observed. Esseva constatate que cortisona e hydrocortisona, marcate con C14, dispare rapidemente ab le cavitate synovial. Illos dispare con le mesme rapiditate como post lor injection intra-articular. Solmente un micre portion del injicite steroides esseva metabolisate localmente. Le transformation de cortisona in hydrocortisona per histos synovial non esseva observate.
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