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Minidose heparin therapy for vasculitis of atrophie blanche

1983; Elsevier BV; Volume: 8; Issue: 1 Linguagem: Inglês

10.1016/s0190-9622(83)70002-2

1097-6787

Robert L. Jetton, Gerald S. Lazarus,

Systemic Lupus Erythematosus Research

Atrophie blanche vasculitis is due to thromboocclusion of dermal blood vessels. A 28-year-old white man with a very severe case of this disease had a complete remission when he was treated with minidose heparin sodium injections. As little as 5,000 U of heparin every 3 days controlled his vasculitis. Further reduction of heparin dose resulted in an exacerbation of disease which was controlled with more vigorous heparin therapy. The role of minidose heparin in cutaneous disease is discussed. Atrophie blanche vasculitis is due to thromboocclusion of dermal blood vessels. A 28-year-old white man with a very severe case of this disease had a complete remission when he was treated with minidose heparin sodium injections. As little as 5,000 U of heparin every 3 days controlled his vasculitis. Further reduction of heparin dose resulted in an exacerbation of disease which was controlled with more vigorous heparin therapy. The role of minidose heparin in cutaneous disease is discussed.