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A case of T-cell chronic lymphocytic leukemia (T-CLL) expressing a peculiar phenotype (E+, OKM1+, leu 1+, OKT3− and IgG EA−)

1983; Wiley; Volume: 52; Issue: 8 Linguagem: Inglês

10.1002/1097-0142(19831015)52

1097-0142

S Tagawa, Ichiro Konishi, Hirohiko Kuratune, Shuichi Katagiri, Nobuhiro Taniguchi, Toshiharu Tamaki, Ryoichi Inoue, Yoshio Kanayama, T Tsubakio, Takashi Machii, Takeshi Yonezawa, Teruo Kitani,

Glycosylation and Glycoproteins Research

AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract A case of chronic leukemia is reported. Malignant cells had the morphology of lymphocytes and an affinity for skin. Cytochemically, they were peroxidase negative, and NaF-resistant α-naphthyl esterase positive. The peripheral mononuclear cells formed E-rosettes and reacted with Leu 1 and OKM1. They were unreactive with OKT3, OKT4, OKT6, OKT8, and OKIa1. The cells did not possess surface IG, C3b receptors, or IgG Fc receptors (EAIgG). They responded weakly to phytohemagglutinin, and did not respond to concanavalin A. 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