Portal de Periódicos da CAPES

The RHOA G17V gene mutation occurs frequently in peripheral T-cell lymphoma and is associated with a characteristic molecular signature

2014; Elsevier BV; Volume: 123; Issue: 18 Linguagem: Inglês

10.1182/blood-2014-02-555946

1528-0020

Rebeca Manso, Margarita Sánchez‐Beato, Silvia Monsalvo, Sagrario Gómez, Laura Cereceda, Pilar Llamas, Federico Rojo, Manuela Mollejo, Javier Menárguez, Javier Alvés, Mónica García‐Cosío, Miguel Á. Piris, Socorro María Rodríguez‐Pinilla,

Ubiquitin and proteasome pathways

To the editor: Peripheral T-cell lymphomas (PTCLs) are a group with poor outcome and nonspecific therapeutic regimens. Recently, Palomero et al[1][1] and Sakata-Yanagimoto et al[2][2] identified a recurrent heterozygous mutation in the RHOA small GTPase gene encoding a p.Gly17Val alteration (G17V)