Artigo Acesso aberto Revisado por pares

Emergence, origin, and function of neutrophil–dendritic cell hybrids in experimentally induced inflammatory lesions in mice

2013; Elsevier BV; Volume: 121; Issue: 10 Linguagem: Inglês

10.1182/blood-2012-07-445197

ISSN

1528-0020

Autores

Shuo Geng, Hironori Matsushima, Takashi Okamoto, Yi Yao, Ran Lu, Kristen Page, Robert Blumenthal, Nicole L. Ward, Toru Miyazaki, Akira Takashima,

Tópico(s)

Immune cells in cancer

Resumo

Key Points Neutrophils differentiate into neutrophil–dendritic cell hybrids upon recruitment to sites of inflammation or infection. Hybrids play dual protective roles against bacterial infection by rapidly clearing bacteria and presenting bacterial antigens to T cells.

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