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The fickle P value generates irreproducible results

2015; Nature Portfolio; Volume: 12; Issue: 3 Linguagem: Inglês

10.1038/nmeth.3288

1548-7105

Lewis G. Halsey, Douglas Curran‐Everett, Sarah L. Vowler, Gordon B. Drummond,

Interpreting and Communication in Healthcare

The reliability and reproducibility of science are under scrutiny. However, a major cause of this lack of repeatability is not being considered: the wide sample-to-sample variability in the P value. We explain why P is fickle to discourage the ill-informed practice of interpreting analyses based predominantly on this statistic.