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Early clinical experience of the safety and effectiveness of Hemospray in achieving hemostasis in patients with acute peptic ulcer bleeding

2011; Thieme Medical Publishers (Germany); Volume: 43; Issue: 04 Linguagem: Inglês

10.1055/s-0030-1256311

1438-8812

Joseph J.�Y. Sung, Derek Luo, Justin C. Y. Wu, J.Y.L. Ching, Francis K.L. Chan, Joseph T. F. Lau, Susan Mack, Richard Ducharme, Patrick Okolo, Marcia I. Canto, Anthony N. Kalloo, Samuel A. Giday,

Esophageal and GI Pathology

Background and study aims: Endoscopic therapy of upper gastrointestinal bleeding remains challenging with conventional endoscopic devices. Use of Hemospray, where a nanopowder with clotting abilities is sprayed onto the bleeding site, had been highly effective for management of arterial bleeding in a heparizined animal model. The safety and effectiveness of Hemospray for hemostasis of active peptic ulcer bleeding in humans was evaluated.