Inappropriate Secretion of Antidiuretic Hormone from Fluphenazine Therapy
1975; American College of Physicians; Volume: 82; Issue: 6 Linguagem: Inglês
10.7326/0003-4819-82-6-811
ISSN1539-3704
AutoresJosé Luis González de Rivera y Revuelta,
Tópico(s)Epilepsy research and treatment
ResumoLetters1 June 1975Inappropriate Secretion of Antidiuretic Hormone from Fluphenazine TherapyJ. L. G. DE RIVERA, M.D.J. L. G. DE RIVERA, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-82-6-811 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe syndrome of inappropriate secretion of antidiuretic hormone (ADH) may be produced by several drugs (1). Phenothiazines have not been implicated so far in the production of this syndrome, although there is a recent report of inappropriate secretion of ADH associated with the structurally related tricyclic antidepressant amitriptyline (2). I wish now to report a case of inappropriate secretion of ADH most likely associated with fluphenazine therapy.The patient was admitted to the Montreal General Hospital in coma, following a convulsive episode. This 33-year-old man had been diagnosed as schizophrenic 7 years ago, and prescribed daily doses of chlorpromazine, which...References1. BARTTER F: The Syndrome of Inappropriate Secretion of Antidiuretic Hormone. Chicago, Year Book Medical Publishers, Inc., 1973 CrossrefGoogle Scholar2. LUZECKY M: The syndrome of inappropriate secretion of antidiuretic hormone associated with amitriptyline administration. South Med J 67:495-497, 1974 CrossrefMedlineGoogle Scholar3. RASKIND M: Psychosis, polydipsia and water intoxication. Arch Gen Psychiatry 30:112-114, 1974 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: J. L. G. DE RIVERA, M.D. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byFluphenazine and Inappropriate Secretion of Antidiuretic HormoneJORGE S. ZUNIGA, M.D., TOBY HAZAN, M.D. 1 June 1975Volume 82, Issue 6Page: 811-812KeywordsChlorpromazineComaIntoxication ePublished: 12 March 2020 Issue Published: 1 June 1975 PDF downloadLoading ...
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