Chromosomes, 11q and cancer: a review
1999; Volume: 187; Issue: 1 Linguagem: Inglês
10.1002/(sici)1096-9896(199901)187
ISSN1096-9896
AutoresJohn Koreth, Christopher J. Bakkenist, James O’D. McGee,
Tópico(s)Genetic factors in colorectal cancer
ResumoThis review aims at providing a general understanding of how the multiple cytogenetic aberrations in cancer cells arise and exemplifies this by considering the specific role of chromosome 11q loci in carcinogenesis. Section provides a theoretical molecular and structural framework for understanding the cytogenetic aberrations described in cancer. Given this background, Section describes advances in the identification and localization of cancer susceptibility genes on chromosome 11q, highlighting ongoing areas of investigation. Copyright © 1999 John Wiley & Sons, Ltd.
Referência(s)