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Potassium Influx Into Rat Erythrocytes: Lack of Effect of Some Adrenal Substances, Especially Aldosterone, Upon It

1967; Oxford University Press; Volume: 80; Issue: 2 Linguagem: Inglês

10.1210/endo-80-2-375

1945-7170

J.G. Llaurado, Ángel Brito,

Ion Transport and Channel Regulation

The dynamics of penetration of K into erythrocytes of the rat has been investigated by means of 42K as a tracer. Results show that there is no significant difference in the K influx value between intact and previously adrenalectomized animals. The mean value for K influx in rat erythrocytes is established as 6.10±0.26 mEq/(hr.l cells). The penetration of K into red cells is 3 times faster in the rat as compared with man. Aldosterone, cortisol, epinephrine and norepinephrine added to the blood were shown to possess no activity on K influx under the present experimental conditions. {Endocrinology80: 375, 1967)