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Implementation of a penicillin allergy skin test

2009; UNIVERSIDADE DE SÃO PAULO; Volume: 45; Issue: 3 Linguagem: Inglês

10.1590/s1984-82502009000300023

2175-9790

Aparecida Tiemi Nagao‐Dias, Ana Carla Pereira, Michelly Freitas e Silva, Eugenie Desiree Rabelo Néri, José Wilson Accioly, Janete Elisa Soares Lima,

Food Allergy and Anaphylaxis Research

The penicillin allergy skin testing is the only accurate and reliable test for penicillin hypersensitivity mediated by IgE. It is useful for identifying patients with doubtful history of allergy. Positive test for major and minor determinants presents a positive predictive value of 50% and negative predictive value of 99%. In Brazil, the Ministry of Health suggests a protocol for in house made reagents, since they are not commercially available. As the referred protocol does not mention some important details about the test procedures, we propose in the present work to implement them, critically evaluating each step in order to allow the protocol establishment at any health service, with quality and safety.