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Haines and Taylor Obstetrical and Gynaecological Pathology

1997; BMJ; Volume: 50; Issue: 7 Linguagem: Inglês

10.1136/jcp.50.7.621-a

1472-4146

M B Heatley,

Prenatal Screening and Diagnostics

Book reviews, Correction concurrence of RDD in a lymph node alternating with areas of atypical mycobacterial infection in an HIV negative patient.The areas typical of RDD comprised a population of S 100 positive histiocytes showing em- peripolesis, while the other area showed the presence of sheets of S100 negative histio- cytes, with areas of necrosis and suppuration, admixed with lymphocytes and plasma cells.Atypical mycobacteria were identified, in this latter area, but not in the area of RDD with appropriate special stains.Although necrosis has been demonstrated in RDD,2 the coexistence of mycobacteria and RDD has not been previously documented.Mycobacteria have, however, been cultured from RDD in bone (Miettinen, Philadelphia, USA, personal communica- tion).Mycobacterial infection may also, uncommonly, manifest as a mycobacterial spindle cell pseudotumour.'This may be mistaken clinically and histologically for a neoplasm.Thus it is feasible that both RDD and mycobacterial spindle cell pseudotumour may be linked by a common aetiological process mycobacterial infection.Clearly this possible pathogenetic link warrants further investigation, with special stains and molecular techniques.