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Template‐Directed Nucleation and Growth of Inorganic Nanoparticles on DNA Scaffolds

2009; Wiley; Volume: 48; Issue: 45 Linguagem: Inglês

10.1002/anie.200903319

1521-3773

Linda A. Stearns, Rahul Chhabra, Jaswinder Sharma, Yan Liu, William T. Petuskey, Hao Yan, John C. Chaput,

RNA Interference and Gene Delivery

DNA origami: A DNA nanotube containing gold-binding peptides can nucleate nanoparticles of a discrete size from soluble chemical precursors. The peptide–DNA nanostructure was used to direct the assembly of an inorganic nanostructure, with gold nanoparticles distributed along the surface of the DNA nanotube (see picture). The resulting nanostructure is an important step forward in the synthesis of programmable inorganic materials by self-assembly. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.