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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

MITOTIC ABNORMALITIES IN SEA URCHIN EMBRYOS EXPOSED TO DACTINOMYCIN

1969; National Academy of Sciences; Volume: 64; Issue: 3 Linguagem: Inglês

10.1073/pnas.64.3.857

ISSN

1091-6490

Autores

Barry I. Kiefer, Charles F. Entelis, Anthony A. Infante,

Tópico(s)

Cephalopods and Marine Biology

Resumo

Dactinomycin at concentrations of 10, 20, 25, and 50 mug/ml causes mitotic abnormalities in sea urchin embryos. Sister chromosome separation is impaired and anaphase bridges are frequently formed. The result is an unequal distribution of the chromosome complement to daughter cells. Possible explanations are discussed.

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