Artigo Revisado por pares

Two-dimensional analysis of copolymers by size-exclusion chromatography and gradient-elution reversed-phase precipitation chromatography

1984; Elsevier BV; Volume: 317; Linguagem: Inglês

10.1016/s0021-9673(01)91700-5

ISSN

1873-3778

Autores

Gottfried Glöckner, J. H. M. van den Berg, Nico Meijerink, Theo G. Scholte, R. Koningsveld,

Tópico(s)

Microfluidic and Capillary Electrophoresis Applications

Resumo

Poly(styrene—co-acrylnitrile) samples were fractionated by size-exclusion chromatography and subsequent high-performance precipitation liquid chromatography (HPPLC) of effluent fractions. HPPLC was performed on a reversed phase column by using a mobile-phase composition gradient with eluting power increasing from 2,2,4-trimethylpentane as a non-solvent to tetrahydrofuran as a solvent. A mixture of two model copolymers of 23 and 30 wt. % acrylonitrile, having molar masses of 825 and 190 kg/mol, respectively, and a commercial SAN copolymer were studied. The correction of retention volumes for the influence of molar mass was determined, and applied in the evaluation of the data for the commercial sample.

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