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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

Combined T and B Cell Acute Lymphoblastic Leukaemia

1974; BMJ; Volume: 4; Issue: 5936 Linguagem: Inglês

10.1136/bmj.4.5936.79

ISSN

0959-8138

Autores

David G. Haegert, JC Cawley, Abraham Karpas, A. H. Goldstone,

Tópico(s)

Acute Lymphoblastic Leukemia research

Resumo

A case of acute lymphoblastic leukaemia in a 17-year-old male is described. The patient had many distinctive features including a very high blast cell count, prominent lymphadenopathy and hepatosplenomegaly, thymic mass, and a fulminant clinical course. Immunological studies on the blast cells using a variety of techniques showed the presence of two distinct subpopulations, one having the surface characteristics of thymus-dependent (T) lymphoid cells and the other those of bursa-equivalent (B) lymphoid cells. The case therefore represents the first example of a combined T and B cell acute leukaemia.

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