Metabolomic analysis of bioactive Amaryllidaceae alkaloids of ornamental varieties of Narcissus by GC–MS combined with k-means cluster analysis
2014; Elsevier BV; Volume: 56; Linguagem: Inglês
10.1016/j.indcrop.2014.03.008
ISSN1872-633X
AutoresLaura Torras‐Claveria, Strahil Berkov, Carles Codina, Françesc Viladomat, Jaume Bastida,
Tópico(s)Alkaloids: synthesis and pharmacology
ResumoOne hundred and six ornamental varieties of Narcissus were analysed by GC–MS in an attempt to determine their alkaloid profile and the relationships between them were explored by multivariate statistical methods. Leaf and bulb tissues were analysed separately. A total of 61 Amaryllidaceae alkaloids and 2 protoalkaloids were identified and quantified. Different alkaloid profiles were found in leaves and bulbs, with leaves showing a higher quantity and more complex profile of alkaloids. Important differences were also found among plant varieties. k-Means cluster analysis determined five clusters based on similarities in alkaloid composition in both leaves and bulbs. The predominant alkaloids were lycorine-type in leaves, and galanthamine-type in bulbs. A correspondence analysis suggested that a global relationship between horticultural divisions of ornamental Narcissus varieties and k-means clusters based on alkaloid composition was unlikely, although some clusters were found to be particularly associated with certain divisions.
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